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✦ 80 patient reports ● Updated 2026-06-24 r/Ozempic, r/Semaglutide, r/GLP1

How Long Before I Start Seeing Weight Loss?

📊 What patients commonly report

Many patients find that weight loss doesn't start right away, especially on the lowest initial doses. About 20-30% might not feel significant hunger relief or see much scale movement in the first few weeks. For those who do see early changes, it's often a couple of pounds, which can be water weight. More consistent and noticeable weight loss, typically 1-3 pounds per week, often begins as doses are gradually increased over several weeks or months.

⚖️ Where experiences differ
Reported as helpful
  • titrating up doses
  • patience on low doses
  • focusing on overall health
  • adequate protein and fiber
Reported as ineffective
  • expecting immediate results
  • stopping too soon
  • comparing to rapid responders
  • ignoring diet alongside meds
📅 Medication, dose & timeline
Wk 1–2
Many patients report minimal or no significant weight loss or appetite suppression, some may notice minor side effects.
Wk 3–4
Initial effects like reduced food noise or slight appetite changes often become more noticeable as the medication accumulates or dose increases.
Month 2–3
Consistent weight loss, often 1-3 pounds per week, frequently begins as doses are titrated to more therapeutic levels.
Month 6+
Significant and sustained weight loss (e.g., 25+ pounds) is commonly reported by patients who respond well and reach optimal doses.
💬 What patients said

"So five days ago I took my first dose of 0.25 mg and I’m not noticing any hunger or food noise relief and no side effects either."

Patient · Ozempic, 5 days

"I started on generic semaglutide a week and a half ago, so I have taken 2x0.25 doses at this point. I have not noticed significant craving reduction, appetite suppression, or weight loss so far."

Patient · Ozempic, 1.5 weeks

"I've been really happy with my Oz journey thus far (started a week before Christmas and I'm currently down 27 pounds, so slightly more than one pound a week)."

Patient · Ozempic, 6 months

"I lost 6 pounds since I started Ozempic in January, is that good? 🥴😂 I have about 15 - 20 pounds to lose"

Patient · Ozempic, A few months

These are patient-reported experiences, not medical advice. Always consult your prescriber for decisions about your treatment.

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